Alexander Zverev crashed out of the Barcelona Open after losing in three sets to lucky loser Nicolas Jarry.
Second seed Zverev lost 6-3 5-7 6-7 (5) to world number 81 Jarry, who saved match point in the deciding set.
The 23-year-old from Chile has made the most of his reprieve after losing in the final round of qualifying to Spain's Marcel Granollers.
Jarry got a second chance in the main draw on Monday against the same opponent and won 7-5 4-6 6-4.
Jarry will play 13th seed Grigor Dimitrov or home favourite Fernando Verdasco in the third round.
Two-time former champion Kei Nishikori recovered from 4-1 down in the first set to beat American Taylor Fritz 7-5 6-2 and will now play Canada's Felix Auger-Aliassime or Tunisia's Malek Jaziri.
Third seed Dominic Thiem progressed after a 6-3 6-3 win over Argentina's Diego Schwartzman.
But 10th seed David Goffin and American 14th seed Frances Tiafoe bowed out after straight-set defeats to Germany's Jan-Lennard Struff and Spain's Jaume Munar respectively.
At the Hungarian Open in Budapest, Serbia's fifth seed Laslo Djere and Australian John Millman, seeded sixth, were among those to reach the second round.
