Britain's Dan Evans was left to rue missed opportunities after losing a hard-fought contest with defending champion Rafael Nadal in the second round of the Rogers Cup in Montreal.
Evans broke Nadal in the first game of a weather-affected match and also led 5-2 in the first-set tie-break, but was unable to press home his advantage against a rusty opponent playing his first match since losing to Roger Federer in the Wimbledon semi-finals.
Nadal won six of the last seven points in the tie-break and overcame a rain delay of almost two hours after taking a 2-0 lead in the second set, the top seed eventually securing a 7-6 (6) 6-4 victory to improve his record in Canada to 35-8.
The 33-year-old Spaniard is seeking a fifth Canadian Masters 1000 title, with his wins evenly split between Montreal (2005 and 2013) and Toronto (2008 and 2018).
Cameron Norrie is also out after he lost 7-6(4), 6-4 to Alexander Zverev but there is a Brit through to the next round after Kyle Edmund ended the six-match winning streak of Nick Kyrgios 6-3, 6-4.
Marin Cilic beat Australian John Millman 6-3, 6-4. He will play the winner between second seed Dominic Thiem and Canadian Denis Shapovalov.
Canadian teenager Felix Auger-Aliassime progressed with a 6-2, 6-7(3), 7-6(3) victory against Vasek Pospisil and he will play countryman Milos Raonic, who reached the 2013 Montreal final, in the next round.
Argentine Guido Pella produced a 6-4, 7-6(4) upset against 15th seed David Goffin and he will meet Moldovan Radu Albot, who beat Gilles Simon of France 6-4, 6-2.
Borna Coric tasted victory for the first time in almost two months, saving two consecutive match points to beat Citi Open semi-finalist Peter Gojowczyk of Germany 2-6, 6-1, 7-6(2).