Nigel Adkins has been installed as favourite to be Hull's next manager after Leonid Slutsky left the role.
Former Southampton and Reading boss Adkins, who was last employed at Sheffield United, was chalked up as the 8/11 jolly with Sky Bet in the immediate aftermath of the club's announcement.
Former West Brom boss Gary Megson is 2/1 with Paul Lambert, who left Wolves in the summer, at 10/1.
A club statement said the decision had been taken "by mutual consent" following a run of seven games without a win in the Sky Bet Championship.
That unwanted streak has left them in 20th position, just three points above the relegation zone. The former Premier League club are 7/2 for a second successive relegation.
Head of club strategy Oleg Yarovinky has also left his role.
Vice-chairman Ehab Allam said: “Leonid has worked tirelessly in his role and has acted with complete honour and been a pleasure to work with. Unfortunately results have not improved as both parties would have hoped and therefore it was agreed for the relationship to come to an end.
“I would like to thank Leonid and Oleg for their efforts here and sincerely wish them well for the future.”
He added the the process of appointing a replacement was already under way.
Slutsky said: "I would like to really thank everyone associated with Hull City from the players and staff to the owner and especially the fans.
“I am very proud to have been through this experience, it was challenging but a very exciting time for me.
"Hull City will always be a part of my heart and I wish the team all the very best for the future.”
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