Glen Durrant has withdrawn from this weekend's International Darts Open after receiving a positive test for Covid-19.
The Premier League champion had been set to compete in the European Tour event in Riesa, but will now be required to isolate in line with Government guidelines.
All other event personnel required to test prior to, or on, their arrival in Riesa have recorded a negative test.
From the original field of qualifiers, Niels Zonneveld has also withdrawn after earlier informing the PDC of his self-isolation requirements after receiving a positive test earlier in October.
Kyle Anderson, Peter Wright, Dirk van Duijvenbode and Ryan Murray had also previously withdrawn from the International Darts Open.
As a result, eight players will come from the Host Nation Qualifier in Riesa on Thursday night to complete the 48-player field for this weekend's event.
Adrian Lewis and Stephen Bunting will return to action in Riesa this weekend after receiving negative results to Covid-19 tests this week, having tested positive ahead of the recent BoyleSports World Grand Prix.
Gerwyn Price will begin his quest for a third consecutive International Darts Open title against either Mario Vandenbogaerde or Ross Smith, with the draw and schedule of play confirmed for this weekend's event.
Price picked up his first European Tour success at the event in 2018 before repeating the feat in 2019, and the Welshman will await the winner of Vandenbogaerde versus Smith, one of 16 first round contest to take place on Friday.
The year's fourth and final European Tour event will be played in front of fans at the Sachsenarena in Riesa from October 23-25, with players battling to make it into the top 32 of the European Tour Order of Merit to qualify for the European Championship.
Former European Tour event winner and German number one Max Hopp will face Jelle Klaasen in the stand-out tie of round one, while Steve West takes on Toni Alcinas in a crucial game in the race to qualify for the European Championship.
The 16 seeded players will enter at the second round stage on Saturday, headlined by the world's top two Michael van Gerwen and Price as well as last weekend's European Darts Grand Prix winner Jose De Sousa.
From the original field of players Kyle Anderson, Peter Wright, Glen Durrant, Dirk van Duijvenbode, Ryan Murray and Niels Zonneveld have withdrawn.
De Sousa and Stephen Bunting - who is returning to action alongside Adrian Lewis this weekend - become seeded players, and six additional Host Nation Qualifiers come into the event.
The line-up for the International Darts Open was completed on Thursday night, with the eight Host Nation Qualifiers including Michael Unterbuchner, Robert Marijanovic and Michael Rosenauer.
The European Darts Grand Prix will be broadcast through PDCTV at video.pdc.tv as well as through a series of bookmakers' websites worldwide.
