Sky Bet's 5/2 favourites Saracens will launch their bid for a third successive Champions Cup against Premiership rivals Northampton.
Holders England booked a Women's Rugby World Cup final appointment with New Zealand after beating France 20-3 in Belfast.
Scotland, who are 16/1 for the Six Nations, have called up Matt Scott and Murray McCallum to their pre-season training camp.
South Africa remain unbeaten in 2017 after they beat Argentina 37-15 in their Rugby Championship opener in Port Elizabeth.
Gregor Townsend has called up seven uncapped players for Scotland's pre-season get-together in St Andrews.
Exeter captain Gareth Steenson is relishing the "new challenge" of starting an Aviva Premiership season as defending champions, although they are 4/1 third favourites with Sky Bet.
In-form Ben Linfoot seeks out the best Value Bet selections on day one of the Welcome To Yorkshire Ebor Festival at York.
Simon Holt previews the action on the opening day of the Welcome To Yorkshire Ebor Festival at York.
It's a fascinating renewal of the Juddmonte International at York on Wednesday and we have a horse-by-horse guide with form and our verdict.
Our Andy Schooler previews Liverpool v Hoffenheim and makes Benjamin Hubner the man to follow in the Champions League qualifier.
Nick Hext brings you betting advice for Wednesday night's action in the second round of the Carabao Cup.
A look at how the Sporting Life recommended bets have performed.