Cristiano Ronaldo grabbed another slice of footballing history as he became the first player to score 400 goals in Europe's top five leagues with his strike for Juventus against Genoa.
It may have been a tap-in, but Ronaldo's fifth Serie A goal of the season took him to the 400 mark - going along with his 84 Manchester United goals in the Premier League and 311 La Liga strikes for Real Madrid.
The goal was not enough to extend Juventus' perfect start in Serie A to nine games though, as Genoa hit back through Daniel Bessa for a 1-1 draw which allowed Napoli to cut the deficit at the top of Serie A to four points with a 3-0 win at Udinese.
Ronaldo is ten goals ahead of his old rival Lionel Messi, who scored his 390th La Liga goal but went off with a broken arm during Barcelona's win over Sevilla.
Ronaldo reached the landmark in the 18th minute at the Allianz Stadium, finishing from close range as Genoa goalkeeper Ionut Radu made a mess of dealing with a corner.
But Genoa enjoyed the better of the second half and got their reward after 67 minute when Bessa headed home.
Juve boss Massimiliano Allegri felt his side already had one eye on Tuesday's huge Champions League showdown with Manchester United at Old Trafford as they lost their 100 percent start to the season.
"We left the game after a good start," he told Sky Sport Italia. "We conceded a goal from a loss of focus. These are situations that shouldn't happen. They're games in which the Scudetto can be won and lost.
"We played, from a certain point of view, with our heads in Manchester. We had to win. We went from frantic to sleeping and vice versa."
Serie A round-up
Napoli took advantage of Juve's slip with a routine win at the Dacia Arena.
Fabian Ruiz, an early replacement for injury victim Simone Verdi, opened the scoring just 14 minutes in, and Dries Mertens doubled the lead from the spot after Nicholas Opoku handled inside the area inside the final 10 minutes.
With the pressure off, Marko Rog then added a third with five minutes to go.
Meanwhile, Roma's troubles grew with a 2-0 home defeat by lowly SPAL, who finished the game with 10 men but looked comfortable all the same.
SPAL took the lead from the penalty spot after 38 minutes. Luca Pellegrini brought down Manuel Lazzari, and Andrea Petagna confidently fired home from the spot.
It was 2-0 11 minutes into the second half when Kevin Bonifazi headed home from a corner, and although Vanja Milinkovic-Savic's bizarre dismissal with 15 minutes left gave Roma hope, they could not take advantage. The SPAL keeper was booked and immediately earned a second yellow for hurling the ball away in dissent.
Defeat leaves Roma sixth, already 11 points off Juve's pace.
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