Rangers earned a tight 1-0 win against St Mirren but Celtic reclaimed top spot with a 3-1 victory over Hearts to set-up a mouth-watering Old Firm derby at Ibrox next Sunday.
Borna Barisic's second-half free-kick gave Rangers a 1-0 Ladbrokes Premiership win over St Mirren in Paisley.
The Croatia international returned to Steven Gerrard's side for the first time in three weeks and broke the deadlock with a dead-ball strike into the top corner just short of the hour mark.
The victory sets up Rangers nicely for the second leg of their Europa League play-off tie against Legia Warsaw at Ibrox on Thursday.
St Mirren struck the post in the first half through Jon Obika but did not offer enough of an attacking threat.
Celtic back on top
Vakoun Bayo claimed two goals on his first start as Celtic beat Hearts 3-1 to ensure they will travel to Ibrox leading the Ladbrokes Premiership.
The Ivory Coast international has had to wait seven months for his full debut but he made his mark as Celtic quickly regained top spot on goal difference following Rangers' 1-0 win over St Mirren earlier in the day.
There was some doubt about whether Bayo got the final touch on both occasions but his determination to get on the end of crosses from James Forrest and Kristoffer Ajer merited the recognition.
Callum McGregor fired a trademark long-range strike in between as Celtic made it 15 goals from their opening three league matches.
Bayo was handed the lone striker's role after working his way up to fitness following hamstring problems which had restricted the 22-year-old to three late appearances off the bench since arriving from Slovakian side Dunajska Streda in January.
The Ivory Coast international showed the Celtic fans he was worth the wait with a lively display and he was centimetres away from a hat-trick when he headed Forrest's cross off the inside of the post just before going off with cramp in the 78th minute.
Fraser Forster also came into the Celtic side after rejoining the club on loan from Southampton in midweek and the goalkeeper saved Conor Washington's 81st-minute penalty only for the Northern Ireland international to net the rebound.
The goal was a mere consolation for Hearts, who denied Celtic any chances in the opening quarter despite losing Michael Smith to injury early on.
Celtic now travel to Sweden for the second leg of their Europa League play-off against AIK before facing Rangers next Sunday.