Manchester City pair Gabriel Jesus and Kyle Walker have tested positive for Covid-19, that will rule the pair out of the Boxing Day clash with Newcastle and, likely, the trips to Everton and Chelsea.
Two unnamed members of staff at the club have also returned positive tests.
Both players featured in City’s 4-1 Carabao Cup win over Arsenal on Tuesday, with City due to host Newcastle in the Premier League on Boxing Day.
A club statement said: “Manchester City FC can confirm that Gabriel Jesus, Kyle Walker, and two members of staff have tested positive for Covid-19.
“All four personnel will now observe a period of self-isolation in accordance with Premier League and UK Government protocol on quarantine.
“Everyone at the club wishes our colleagues a speedy recovery over the Christmas period ahead of their return to work, training and competition.”
Under Premier League regulations, players or club staff who have tested positive will self-isolate for a period of 10 days.
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