Chelsea are now FA Cup favourites after they drew Southampton while Man Utd will play Tottenham in the semi-finals.
That match will see new Saints boss Mark Hughes take on one of his former clubs.
Southampton won 2-0 at Wigan of Sky Bet League One on Sunday in Hughes' first game in charge
The semi-finals will take place over the weekend of April 21-22.
FA Cup semi-final draw
- Manchester United v Tottenham Hotspur
- Chelsea v Southampton
Sky Bet's outright FA Cup odds
Odds correct at 1935 GMT on 18/03/2018.
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