Arsenal will still be on cloud nine after their derby win and it'll take every trick in Jose Mourinho's book to get a result against the Gunners at Old Trafford.
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Manchester United v Arsenal (2000 KO, BT Sport)
There are three places and eight points between Arsenal and Manchester United, but an even greater gulf in atmosphere and hope surrounding both clubs and their respective managers going into Wednesday's showdown.
Jose Mourinho is still enduring tough times at Old Trafford with their chances of even scraping into the top four already looking bleak given they're eight points off the pace with over a third of the season already gone.
Unai Emery, in contrast, can do no wrong at Arsenal with the Gunners unbeaten in 19 games and on the back of their pulsating north London derby win over Tottenham.
This 'new' Arsenal has shown fight, character and spirit - three things all missing at the end of Arsene Wenger's protracted departure and that coupled with their obvious attacking weapons means they're a dangerous outfit for United to deal with.
Still, Arsenal have questions to answer, namely if they'll be able to recover from Sunday and get back up for another huge game so quickly, or whether it'll be a game too far - especially if Mourinho's side make it into a physically bruising encounter.
Prediction: Manchester United 1-2 Arsenal (Sky Bet odds: 9/1)
Both teams have scored in all of Arsenal's away games in the league this season and only Crystal Palace have failed to score at Old Trafford - and still got a draw! United usually turn up for these games regardless of their form, but having watched a lot of the two teams this looks a brilliant opportunity for the Gunners to get a rare Old Trafford win.
Best bet: Arsenal draw no bet at 11/10
It's so tempting to pile in to Arsenal at around 2/1 for the win as they look a class above anything United have offered up for most of this season. United were torn apart by Spurs at home early in the season and that could easily happen again, but Mourinho has a habit of pulling out a result in these games and after recent displays a draw would be a result for him, so just in case....
Goals: Pierre-Emerick Aubameyang anytime scorer at 7/4
Cenk Tosun, Fernando Lorente and Dominic Solanke - just a few players who are a shorter price than the Premier League's top scorer to find the net at Old Trafford - where United have kept two clean sheets in ten games against Valencia and Young Boys. His record is phenomenal, he's looking razor sharp and, perhaps his most important credential, he's also our Golden Boot tip for this season.
RequestABet: Both teams to score, Martial & Aubameyang 1+ shots on target, 10+ corners, Man Utd 30+ booking points at 9/1
There should be plenty going on at Old Trafford, there usually is when arsenal play away from home and there's no reason why all of these don't come into play.
Manchester United v Arsenal - Opta stats
- Manchester United are unbeaten in their last 11 home Premier League games against Arsenal (W8 D3), since a 0-1 loss in September 2006.
- Arsenal lost both Premier League meetings with Manchester United last season – they last lost three in a row against them in November 2012.
- Arsenal have only scored more than once in three of their last 39 away league games against Man Utd – and they’ve lost all three of those games (2-4 in November 1984, 2-8 in August 2011 and 2-3 in February 2016).
- This is the first time Man Utd have hosted Arsenal in a midweek Premier League match since May 8th 2002, when Arsenal won 1-0 to clinch the title thanks to a Sylvain Wiltord strike.
- Arsenal have lost their last three midweek Premier League games (Tuesday, Wednesday, Thursday), conceding three goals in each defeat (vs Swansea, Man City and Leicester last season).
- Arsenal have scored at least twice in all six of their away league games this season – only Watford last term have scored 2+ goals in their first seven games on the road in a single Premier League campaign.
- Manchester United have conceded 23 goals in their 14 league games this season; it wasn’t until their 30th Premier League game of 2017-18 that they conceded their 23rd goal last season.
- Arsenal are unbeaten in their last 19 games in all competitions. They last went 20 without defeat between April/November 2007 (28 games).
- Arsenal have won four of their six away Premier League games this season (D1 L1) – as many as they had in 19 on the road last term (W4 D4 L11).
- Man Utd boss Jose Mourinho has never previously lost in five meetings with Arsenal manager Unai Emery (W4 D1, all in La Liga), with this their first meeting since October 2013 (Mourinho’s Real Madrid beating Emery’s Sevilla 4-1).
- Arsenal’s Pierre-Emerick Aubameyang has scored with each of his last 10 shots on target in the Premier League.
Odds correct as of 1735 GMT on 5/12/18