World number seven Barry Hawkins suffered a shock defeat to Sam Craigie in the last 64 of the Gibraltar Open.
Hawkins, the only top-10 player taking part in the tournament, breezed past Chris Wakelin in his first match but was then beaten 4-1 by Craigie.
The world number 81's run was ended in the evening session with a last-32 defeat to Cao Yupeng, who had earlier seen off Yuan Sijun and Matthew Stevens.
Kyren Wilson is the highest-ranked player left in the draw. The world number 12 saw off Mark Joyce 4-1, compiled breaks of 135 and 107 to beat Daniel Wells by the same score before recording a 4-2 win over Andy Hicks in the evening.
Elsewhere on Friday, 1997 world champion Ken Doherty reeled off three victories, lastly overcoming Dominic Dale 4-3 in a match that came down to the final black.
World number 14 Stuart Bingham produced breaks of 140 and 130 as he won three matches to reach the last 16, where he is also joined by Matthew Selt, Anthony McGill, Lee Walker and Yu Delu.
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