Wasps have announced winger Christian Wade has retired from rugby union amid reports that he is to try to make a move into the NFL.
The 27-year-old has been released from his contract on confidential terms, Wasps said in a club statement.
"After playing nine years of professional sport for Wasps, I've decided to leave for personal reasons," said Wade, who won his only England cap against Argentina in 2013.
"I would like to thank Wasps chairman Derek Richardson and Dai (Young, director of rugby) for their support, consideration and understanding in what is the most difficult decision of my life.
"I have loved the sport since I was introduced to it at the Royal Grammar School in High Wycombe.
"I would therefore like to thank everyone who has played a part in shaping my career.
"Rugby has privileged and honoured me with so many wonderful memories that will stay with me for the rest of my life.
"Finally, I want to thank my Wasps family: the club, my team-mates and especially the fans - you have always been superb to me. I wish everyone here all the very best for the future."
Wasps are currently third in the Gallagher Premiership and bottom of their Heineken Champions Cup group after Saturday's 35-35 draw with Bath.
"It's very disappointing to lose a player of Wadey's quality at this stage of the season," Young said.
"The club held numerous discussions with him to try and convince him to keep pushing forward with Wasps but in the end it was clear this is the path he wished to go down.
"The club nevertheless wants to wish him all the best with his future career path and put on record our thanks for the contribution Christian has made to Wasps Rugby."