British number two Cameron Norrie was beaten in straight sets 6-2 7-5 by Italian qualifier Lorenzo Sonego in their third-round match at the Rolex Monte-Carlo Masters.
The 23-year-old, ranked 56 in the world, had progressed to the last 16 after a hard-fought victory over Hungary's Marton Fucsovics.
However, Norrie was soon on the back foot against Sonego, the world number 96, who delivered two early service breaks to take control of the opening set at 4-0.
Norrie produced a recovery in the second set, having trailed 3-1 to level at 5-5, but Sonego rallied to immediately break back before going on to close out victory with a love service game and secure a place in the quarter-finals.