Liverpool striker Diogo Jota has died in a car crash in north-west Spain, aged 28.
The Portugal international's 26-year-old brother Andre Silva, a footballer for Portuguese second division club Penafiel, also died.
The Spanish Civil Guard told the BBC the incident took place at 00:30 local time on Thursday in the Spanish province of Zamora.
Jota married the mother of his three young children on June 22, sharing images of the wedding on his social media in recent days.
"The Portuguese Football Federation and the entire Portuguese football community are completely devastated by the death of Diogo Jota and his brother André Silva, this morning in Spain," said the FPF in a statement.
"Much more than a fantastic player, Diogo was an extraordinary person, respected by all his team-mates and opponents, someone with an infectious joy and a reference in the community itself.
"The Portuguese Football Federation expresses its deepest condolences to the family and friends of Diogo and André Silva, as well as to Liverpool FC and FC Penafiel, the clubs where the players played respectively.
"The Portuguese Football Federation has already asked UEFA for a minute's silence this Thursday, before our team's match against Spain in the Women's European Championship.
"We have lost two champions. The passing of Diogo and André Silva represents an irreparable loss for Portuguese football and we will do everything we can to honour their legacy every day."
Jota started his career with Portuguese club Paços de Ferreira, moving to Atletico Madrid in 2016.
He never made an appearance for Atleti, spending a campaign on loan at both Porto and Wolves, helping the latter win promotion from the Championship before joining permanently and playing a key role over the next two seasons in the Premier League.
He joined Liverpool in 2020 and during five years at Anfield won the Premier League, FA Cup and EFL Cup, scoring 65 goals in 182 appearances.
This summer he won a second Nations League title with Portugal as they beat Spain on penalties in the final.
"Liverpool Football Club are devastated by the tragic passing of Diogo Jota," said the club in a short statement.
"Liverpool FC will be making no further comment at this time and request the privacy of Diogo and Andre’s family, friends, teammates and club staff is respected as they try to come to terms with an unimaginable loss.
"We will continue to provide them with our full support."