England seamer Toby Roland-Jones was unable to take the field for the start of day two in Middlesex's County Championship match at home to Lancashire.
Roland-Jones, who had earlier made a half-century, had to leave the field mid-over at Lord's on Tuesday with an apparent back problem, having taken two wickets.
Middlesex were hoping he would be fit to return on the resumption, but then shortly before start-of-play announced via Twitter that he would not do so.
Roland-Jones has impressed in his maiden Test summer, taking 17 wickets in four matches against South Africa and West Indies.
The 29-year-old is expected to be included in England's squad for the Ashes with the selectors set to confirm the tour party towards the end of next week.
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