Former England boss Steve McClaren is the favourite with Sky Bet to take charge of Leeds after Thomas Christiansen was sacked as head coach.
Christiansen's departure means Leeds are looking for what will be a 10th manager since the sacking of Simon Grayson six years ago.
Grayson is the second-favourite at 3/1 with Sky Bet to return to Elland Road after leaving Sunderland earlier this season.
Former Leeds midfielder Gordon Strachan can be backed at 11/2 to return to his former club and Barnsley boss Paul Heckingbottom is on offer at 6/1 to switch to a rival Yorkshire club.
Christiansen, who took the job last summer, has paid the price for a horror dip in form which culminated in Saturday's 4-1 Sky Bet Championship defeat at home to Cardiff.
The Whites have failed to win since their 2-1 Boxing Day victory at Burton, a run which has seen them fall out of the running for the play-offs and also be knocked out of the FA Cup by Newport of Sky Bet League Two.
Christiansen, a former Barcelona and Spain striker of Danish descent, made his name in Cyprus and seemed to immediately settle in England, with Leeds topping the table in early September.
However a run of one win in eight put the skids on their promotion charge and, although they recovered in November and December, their current seven-game winless run has seen Radrizzani pull the trigger.
"Leeds United can confirm that head coach Thomas Christiansen has left the club," a statement read.
"Chairman Andrea Radrizzani and the board of directors would like to thank Thomas and his staff for their hard work over the past eight months."
Next Leeds United manager contenders
Steve McClaren (8/11 favourite with Sky Bet)
Well-travelled, and available, McClaren would fit Leeds' desire to have a head coach work under director of football Victor Orta. McClaren has held many jobs, to varying degrees of success, and is a Leeds fan. He was in attendance for Saturday's loss to Cardiff.
Simon Grayson (3/1 with Sky Bet)
Sacked by Sunderland earlier this season, Grayson would be a popular choice at Elland Road. Sunderland apart, he has rarely done a bad job wherever he has been, including a three-year spell at Leeds when he won promotion from Sky Bet League One.
Gordon Strachan (11/2 with Sky Bet)
Another Leeds old boy, Strachan captained United to the First Division title in 1992. Has gone on to have a long career in management, including a successful spell at Celtic. Was most recently in charge of Scotland.
Paul Heckingbottom (6/1 with Sky Bet)
Would be a strange appointment given he recently signed a new deal at Barnsley, where he has earned a reputation as a fine manager in his two years in charge.
Odds correct at 0640 GMT on 05/02/18.
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