Juan Martin del Potro powered through to only his second Wimbledon quarter-final after beating Gilles Simon.
Del Potro, whose best run at the All England Club saw him reach the semi-finals in 2013, triumphed 7-6 (7/1) 7-6 (7/5) 5-7 7-6 (7/5) to set up a last-eight meeting with Rafael Nadal.
The fourth-round match resumed on Tuesday afternoon after bad light had stopped play on Monday with the Argentinian leading by two sets to one.
Simon had an early break in the fourth set, but Del Potro hit back and was on the verge of victory until the Frenchman saved four match points to take it to another tie-break.
Del Potro raised his game again, though, claiming his third tie-break success of the match to book his date with Nadal.
While Nadal and Del Potro will face off on Centre Court, Roger Federer's residency on the main court at Wimbledon will come to an end on Wednesday.
The eight-time champion played all seven of his matches last year on the main stadium court and was also a fixture there for his first four contests of this fortnight's championships.
However, Federer's quarter-final against South African Kevin Anderson has been allocated a Court One slot.
Tournament organisers announced that last-eight clash would open play at 1pm on the second largest show court, followed by the match between big servers Milos Raonic and John Isner.
Centre Court action begins with Novak Djokovic taking on Kei Nishikori, followed by Nadal's match against Del Potro.