Barry Hawkins, Luca Brecel and Jack Lisowski were notable casualties in Saturday's action at the Gibraltar Open.
Brecel, Belgium's rising star, was beaten 4-3 by Liam Highfield in round three while Hawkins crashed out at the same stage and by the same score to the unheralded Ashley Carty.
Lisowski survived that round but lost 4-3 in the fourth to Gary Wilson, who then saw off veteran Ken Doherty 4-1.
Kyren Wilson dropped only two frames as he beat Jordan Brown, Jimmy White and Ross Muir but Stuart Bingham was taken the distance by Eden Sharav before winning their last-32 match 4-3.
Defending champion Ryan Day is through to the last 16 after wins over Lukas Kleckers, Noppon Saengkham and Elliot Slessor while Robert Milkins and the in-form David Gilbert also made it through.
Wilson, Bingham and Gilbert are competing for the final two places in next week's Tour Championship in Wales, contested by the top eight on the one-year world ranking list.
Wilson told World Snooker: "It's quite nice that we're all still in, it gives a little edge to the tournament and makes Sunday more exciting."