Exeter centre Henry Slade will miss the sold-out Gallagher Premiership clash with Saracens at Sandy Park through injury.
The England international was forced off during the first half of Saturday's win at Leicester after taking knocks to both of his ankles.
He left Welford Road on crutches following the Chief's 33-21 victory and the 26-year-old has undergone scans to assess the severity of his injuries.
Exeter director of rugby Rob Baxter told the club's official website: "Sladey's going to be out for a little while.
"He's picked up injuries to both of his ankles. He tried hobbling along with one, until he picked up the second.
"The second injury is more of a concern as it's an injury in and around an old injury, which he had had previously plated. Right now, he's continually being assessed and we will know more in due course.
"It is, however, not something he will be able to get over in a week or two - it's more significant than that."
Eddie Jones names England's Six Nations squad on January 20 with Slade now considered a doubt.
