Get team news, head-to-head statistics and more ahead of the latest Aviva Premiership action.
Saturday, May 5
Bath (8) v London Irish (12)
Bath prop Anthony Perenise makes his 100th appearance for the club and there are returns for captain Matt Garvey and wing Cooper Vuna.
Relegated London Irish give an Aviva Premiership debut to Ben Loader on the left wing. New Zealand prop Ben Franks is named on the bench.
Last season: No corresponding fixture
Last six league matches: Bath W L L L L W; London Irish W L L W L L
Top try-scorers: Matt Banahan, Semesa Rokoduguni (Bath) 7; Alex Lewington (London Irish) 8
Top goal-scorers: Rhys Priestland (Bath) 186; Tommy Bell (London Irish) 128
Harlequins (10) v Exeter (1)
Harlequins made three changes following their defeat at Worcester with injuries to Jamie Roberts and Joe Marchant creating opportunities in midfield for James Lang and Alofa Alofa.
Exeter have rotated their squad including four changes to the pack that among them sees the return of Thomas Waldrom and Luke Cowan-Dickie. Olly Woodman is restored to the left wing and Jack Nowell moves to outside centre.
Last season: Harlequins 26 Exeter 39, Exeter 36 Harlequins 25
Last six league matches: Harlequins L W L L L L; Exeter W W W W W W
Top try-scorers: Charlie Walker (Harlequins) 9; Sam Simmonds (Exeter) 12
Top goal-scorers: Marcus Smith (Harlequins) 187; Gareth Steenson (Exeter) 201
Newcastle (4) v Wasps (3)
Joel Hodgson's knee injury means Josh Matavesi is moved to fly-half by Newcastle. Falcons star back Vereniki Goneva is injured and so misses out as one of eight changes.
Kyle Eastmond makes on his seventh appearance of the season having completed a six-week ban and recovered from calf and hamstring injuries. He displaces Jimmy Gopperth at inside centre and James Haskell starts at six.
Last season: Newcastle 30 Wasps 34, Wasps 31 Newcastle 6
Last six league matches: Newcastle W W W L W W; Wasps D W L L W W
Top try-scorers: Vereniki Goneva (Newcastle) 13; Christian Wade (Wasps) 12
Top goal-scorers: Toby Flood (Newcastle) 133; Jimmy Gopperth (Wasps) 150
Northampton (9) v Worcester (11)
Ben Foden makes his 250th and final appearance for Northampton, captaining the side from full-back. James Grayson starts at outside centre.
Worcester wing Perry Humphreys makes his first appearance since January after recovering from a knee problem and centre Will Butler makes his Premiership debut.
Last season: Northampton 24 Worcester 14, Worcester 17 Northampton 18
Last six league matches: Northampton L L L L W L; Worcester L L L W L W
Top try-scorers: Mike Haywood (Northampton) 6; Josh Adams (Worcester) 13
Top goal-scorers: Harry Mallinder (Northampton) 114; Chris Pennell (Worcester) 86
Sale (7) v Leicester (5)
Munster-bound Sale full-back Mike Haley returns from suspension for his final match for the Sharks. Josh Strauss displaces Ben Curry in the back row.
Matt Toomua has been ruled out by injury so Mathew Tait starts at inside centre for Leicester, who make two additional changes by recalling wing Jonah Holmes and flanker Mike Williams.
Last season: Leicester 41 Sale 18, Sale 34 Leicester 30
Last six league matches: Sale L W W W L L; Leicester W W W W L L
Top try-scorers: Byron McGuigan (Sale) 12; Johnny May (Leicester) 9
Top goal-scorers: Alan MacGinty (Sale) 170; George Ford (Leicester) 231
Saracens (2) v Gloucester (6)
Billy Vunipola misses out for Saracens because of a hamstring injury and there are six changes to the starting XV including a new-look front row in Richard Barrington, Schalk Brits and Juan Figallo.
Former Wales hooker Richard Hibbard could make his 100th appearance for Gloucester if he is used off the bench. Only flanker Lewis Ludlow survives from the pack that took the field against Bath.
Last season: Gloucester 31 Saracens 23, Saracens 24 Gloucester 20
Last six league matches: Saracens L L W W W W; Gloucester D L W L W L
Top try-scorers: Ben Spencer (Saracens) 8; Henry Trinder (Gloucester) 6
Top goal-scorers: Owen Farrell (Saracens) 315; Billy Twelvetrees (Gloucester) 167