Raffle Prize (9/2) defied a three-pound penalty to come out on top in the battle of the Royal Ascot winners in the Duchess Of Cambridge Stakes at Newmarket.
Frankie Dettori grabbed the stands' rail and the lead as soon as the stalls opened aboard the Queen Mary heroine who never looked in danger as she became the second winner in as many races to set a new track record.
Albany victor Daahyeh tried to throw down a meaningful challenge approaching the final furlong but never landed a telling blow and had to settle for the runner-up berth, a length-and-three-quarters adrift.
Divine Spirit raced prominently throughout and took third for Godolphin.
Johnston said on Racing TV: "Obviously the second horse had beaten her before first time out and she was the talk of the town but that was first time out. She (Raffle Prize) showed fantastic speed that day and just got tired so she had every right to come on.
"I hadn't expected to turn the tables but I hoped we could and she's clearly better over six (furlongs). Frankie said she's improved and better over six and we want to go for the Morny then it's up to you.
"I think that will be up to the owner but she's won two Group Twos so we'll have to have a shot at a Group One next. We'd be taking on the colts but quite often the fillies do well there.
"There are no similarities to Attraction (who won this race for the yard before winning the 1000 Guineas the following spring) but a lot of similarities in temperament.
"She's a laidback filly and just goes through the motions at home. She's quiet going down to the start and doesn't get on her toes but then she bursts out of the stalls and is very fast."
Sky Bet cut the winner to 20/1 from 33s for the QIPCO 1000 Guineas. Head of Sports PR Michael Shinners said: "Raffle Prize did well to defy her penalty and she looks as good a juvenile filly as we've seen this season."
Varian said of Daahyeh: "She ran a good race. We are always disappointed when they don't win, but she ran a good race. Full credit to the winner as she has probably improved since we beat her in May. We could never quite make up the ground, but I thought David (Egan) gave her a good ride.
"The fillies in front of her didn't quite take us to the winner, so we have had to go wide into the middle of the track and she could never make up the ground. She finished off well and shaped as though she might get a furlong further. I don't think she has harmed her reputation and she remains an exciting prospect.
"We will make sure she is OK. She has got all the options. There is not really much at Goodwood for her. "