Jadon Sancho, Mason Mount and James Maddison have been handed their first senior England call-ups as Gareth Southgate doubled down on his focus on youth in arguably his boldest squad selection to date.
Fresh from signing a new deal through to the 2022 World Cup in Qatar, the 48-year-old raised eyebrows on Thursday with his 25-man selection for the Nations League double-header in Croatia and Spain.
Exciting Borussia Dortmund 18-year-old Sancho has been selected for this month's fixtures, and so too Mount after shining for Sky Bet Championship side Derby since joining from Chelsea on loan.
Maddison has been rewarded for his fine start to life at Leicester and Southgate is ready to unleash the youngsters against some of the world's best.
"Well, it is (a big call) but I think it aligns with what we've done over the last 18 months, really," the Three Lions boss said.
"We've got a few injuries in the midfield in particular - Dele (Alli), Jesse (Lingard) and Ruben (Loftus-Cheek) have been missing - and Fabian Delph, so there is an opportunity there.
"Then we have a decision on which way we want to use that opportunity. We think there are some exciting young players that we've been tracking, either through their clubs or our junior teams.
"It is a great opportunity for us to look at them. We feel that we are always conscious of the balance of how quickly we put those young players in and raise expectation around them and make sure that we don't detrimentally affect their development.
"But we think they are performing well with their clubs, they're confident players.
"We'd like to work with them now - they get an understanding of how we work, we get a closer look at them.
"Quite a few of them have trained with us at various times here anyway so we're excited to see them."
Injuries and a lack of game-time have led to Southgate's changes as much as the form of those called-up, with Adam Lallana another big name dropped this time.
Harry Winks, capped once, has returned to the senior team the day after starting for Tottenham against Barcelona in the Champions League, while uncapped Watford midfielder Nathaniel Chalobah is back in the squad after recovering from a long-term knee injury.
In addition, Ross Barkley's upturn in fortunes at Chelsea means he is in line to win his first cap since the friendly against Australia in May 2016.
"Well, he's had a long period injured at Chelsea last year, so that wasn't a reflection on the quality of the player that he hadn't been with us, but he wasn't getting any football, really," Southgate said.
"This year he's started the season in the team at Chelsea.
"He's a player that we know has good technical quality, is grasping the tactical side of the game - I was interested to read his interviews this morning on that - so it's a good opportunity for him to come in.
"As I say, one or two of those opportunities might not have been there if we'd had other players available.
"But as always, when you get opportunities within the squad - people have come in, in the past, and done well and they stay in. That's the way we work."
Southgate spoke well of Daniel Sturridge after overlooking the Liverpool striker and insisted the door is still open to Joe Hart, despite plumping for uncapped Marcus Bettinelli and Alex McCarthy along with Jack Butland and Jordan Pickford.
Asked if the Burnley goalkeeper's international career was over, the England boss said: "No, not at all. It's continuity from the squad we picked last month.
"Jack started our last game so to suddenly leave him out of the squad because he's playing in the Championship wouldn't be appropriate I think.
"From Joe's perspective, we don't need to see Joe in a game at this stage to know what he can do.
"I think it's great that he looks very settled. The move to Burnley has obviously worked for him - he looks confident in his game.
"We're looking at some other young goalkeepers that we need to know a bit more about.
"Jordan obviously did superbly well for us in the summer, but there's no way that, long term, Joe is ruled out.
"I just think at this moment in time it makes sense to look at the other three guys underneath Jordan."
🗒️ Some exciting young names in Gareth Southgate's latest @england squad for the #NationsLeague games...
— Sporting Life Football (@SportingLifeFC) October 4, 2018
Mount
Sancho
Maddison
Chalobah
Winks#ThreeLions pic.twitter.com/e5mpWb9I8Q
The 18-year-old former Manchester City youth team player has proved a big hit following his move to Borussia Dortmund. Sancho, rated as one of the most exciting prospects in Europe, has been rewarded with a new deal from the Bundesliga club - and helped create a goal in the midweek Champions League win over Monaco.
England Under-21 midfielder Maddison has impressed for Leicester in his debut Premier League campaign following a £24million summer move from Norwich. The former Coventry trainee has hit three goals so far and provided two assists to put himself in the senior England picture.
Southgate had been keeping a close eye on the progress of England Under-21 midfielder Mount, the 19-year-old on loan at Sky Bet Championship side Derby from Chelsea. Mount, with five goals, has been a regular starter for Frank Lampard's men.
Midfielder Barkley has found himself back in the picture at Chelsea under Maurizio Sarri, having started the Community Shield against Manchester City. The 24-year-old is in contention to earn a first England cap since the friendly against Australia in May 2016.
Hornets midfielder Chalobah could well have earned a first senior England appearance already but for a serious knee injury which sidelined him for most of last season. Chalobah has been eased back into first-team action by Watford, but did start both Carabao Cup ties.
Tottenham midfielder Winks will be looking to add to his one cap so far, which came in the final 2018 World Cup qualifier away against Lithuania during October 2017. The 22-year-old has made eight appearances for Spurs this season - the last one coming up against Barcelona star Lionel Messi in the 4-2 Champions League defeat at Wembley on Wednesday night.