League One leaders Wigan will hope history can repeat itself after landing an FA Cup rematch with Manchester City in the fifth round draw.
The DW Stadium clash will stir memories of the 2013 final when Wigan - then sliding out of the Premier League - snatched a stunning late winner through a Ben Watson header.
Despite what appears a favourable draw, City remain 20/1 for the quadruple with Sky Bet, who make them just 100/30 for a domestic treble with the Champions League considered their biggest hurdle.
In the pick of the other ties, new Swansea boss Carlos Carvalhal will face a quick return to his former club Sheffield Wednesday provided the Swans beat League Two Notts County in a replay.
Manchester United will travel to either Huddersfield or Birmingham, who battled out a 1-1 draw at the weekend and face a replay at St Andrew's.
Chelsea face Hull at Stamford Bridge while Millwall could face Tottenham in a repeat of last season's quarter-final provided they win replays over Rochdale and Newport respectively.
West Brom and Southampton meet in an all-Premier League clash, Sheffield United travel to Leicester, while Brighton face 1987 winners Coventry.
Sky Bet's outright odds: 9/4 Man City, 7/2 Chelsea, 4/1 Man Utd, 5/1 Tottenham, 14/1 bar
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FA Cup fifth-round draw
Sheffield Wednesday v Notts County or Swansea
West Brom v Southampton
Chelsea v Hull
Leicester v Sheffield United
Huddersfield or Birmingham v Manchester United
Millwall or Rochdale v Newport or Tottenham
Brighton v Coventry
Wigan v Manchester City
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