Jofra Archer's hat-trick in a dramatic last over saw Sussex to a 12-run win over Middlesex in the Vitality Blast South Group match at Lord's.
Archer claimed the vital wicket of Eoin Morgan just as England's white-ball captain threatened an unlikely win for the hosts with 90 off 56 balls, his highest score in T20 cricket.
The Barbadian-born seamer then bowled John Simpson before completing his hat-trick by trapping James Fuller lbw.
The drama came after a blistering half-century off just 19 balls from Phil Salt and 49 from debutant Delray Rawlins had helped the visitors post a challenging total of 168.
Victory was the Sharks' fourth of the campaign, but defeat for Middlesex left them struggling to qualify.
Smarting from defeat at the hands of Gloucestershire 24 hours earlier where their batting failed them, Jason Gillespie's side were given an electrifying start by Salt.
The Welshman set the tone by hitting successive sixes in the first over, bowled by Steven Finn, a long-hop pulled over square-leg, followed by one drilled over long-off.
Finn claimed some recompense when catching the dangerous Luke Wright at backward point off Ravi Patel, but Salt continued his onslaught, twice depositing Ashton Agar into the crowd, the second maximum seeing him to 50.
Agar bowled him next ball with a quicker delivery, the first of three wickets in as many overs for the Australian, but with the victims costing more than 10-an-over Sussex had 98 on the board at halfway.
Rawlins took up the quest for runs, one reverse sweep into the stands off Agar probably the shot of the innings.
At one stage it looked as if Sussex's highest score of 202 in the format at Lord's five years ago might be under threat but to their credit a Middlesex attack pummelled for 229 by Somerset in their last outing fought back well.
Fuller was the first to apply the brakes before Patel bowled Ben Burgess to leave Sussex 150 for six.
Then Tom Barber took centre stage, having Rawlins caught by Fuller out in the deep, one short of a deserved 50, though the catcher and Nick Gubbins collided in pursuit of the ball, Fuller doing well to cling on as he fell.
Left-armer Barber would go on to claim the scalps of David Wiese and Chris Jordan to make it three in six balls, the second match running he had taken a trio of wickets in an over.
And Sussex were all out with two balls left of their innings when Rashid Khan was caught on the fence to give Fuller a deserved wicket.
Middlesex made a poor start, losing dangerman Paul Stirling for nought to the second ball of the innings, Wright producing a fine diving catch at cover off Wiese.
And when Max Holden fell in the fifth over with just 25 on the board Middlesex were in trouble.
Morgan's counter-attack was breathtaking with two sixes and five fours, one a gorgeous reverse-sweep, helping glean 31 in just two overs.
He and Nick Gubbins raised a 50-stand in 30 balls, of which Morgan contributed 42.
Gubbins was stumped off Danny Briggs for 25, but Morgan went to 50 off 32 deliveries.
Another huge six off Rashid followed, but the run-rate kept climbing and Stevie Eskinazi was bowled by Jordan in the quest for quick runs.
While Morgan remained, Middlesex were still in the game and another huge six took the equation down to 16 off the final over.
However, he holed out to Jordan in the deep as Archer, with figures of three for 25, claimed his treble.
Archer said: "To get a hat-trick, I can't really believe it - especially for a domestic T20 as well, it's not like it's an international game and I'm really honoured to hear that they want to put my shirt in the museum here at Lord's."
Ish Sodhi turned the match on its head as Nottinghamshire completed their own version of 'The Hundred' with a thrilling nine-run victory over Derbyshire in a Vitality Blast game at Trent Bridge.
Sodhi took four for 17, his best figures for Notts, as the Falcons fell away after looking on course to win their fifth straight match.
The visitors had been 93 for two, in pursuit of a victory target of 167, but Sodhi's spell changed the complexion of the evening.
His second wicket had been that of Wahab Riaz, who blitzed his way to 53, his highest score in the format, making his runs from only 31 balls with four fours and four sixes.
Earlier, Tom Moores scored 48 as Notts recorded their 100th victory in the domestic T20 competition, becoming only the second county to reach that landmark.
Moores scored his runs from 34 balls, with four fours and three sixes, as the defending champions made 166 for five after winning the toss and opting to bat first.
Dan Christian also weighed in with an unbeaten 39, sharing a stand of 73 with Billy Root.
Lockie Ferguson was the pick of the Derbyshire attack, taking two for 15.
The Falcons sank after the fall of Riaz's wicket and could only reach 157 for eight as the overs ran out.
Ferguson had put Notts under early pressure by bowling both Riki Wessels and Jake Libby but Moores hit Ravi Rampaul for consecutive sixes as the power-play overs ended on 37 for three.
Samit Patel was dropped on 13 by Billy Godelman but could not capitalise on his good fortune and only added nine more before Hardus Viljoen knocked over his off pole.
Moores fell to Matt Critchley's first delivery but Christian and Root gave the back end of the innings some impetus.
Christian hit three maximums and Root also cleared the ropes as the Outlaws finished strongly.
Patel, who has featured in 96 of the Outlaws' wins, removed Calum MacLeod in the opening over but Riaz and Billy Godelman made the chase seem a formality before Sodhi came on.
The New Zealand leg-spinner trapped Godleman lbw, had Riaz caught behind, bowled Gary Wilson and had Wayne Madsen caught in the deep.
Harry Gurney, with two for 33, ensured that Notts held on for the win, meaning that his side could celebrate an important two points and their place in history as the second team to reach the century milestone - getting there 13 days after Lancashire achieved the feat.
Durham took a step towards the quarter-finals of the Vitality Blast by notching their fifth win in a row in the competition, defeating Northamptonshire by 75 runs at Emirates Riverside.
The home side were inserted by the winless Steelbacks, and although they were unable to get off to a flying start, Paul Collingwood's fifty - along with quickfire scores in the twenties from Liam Trevaskis and James Weighell - guided Durham to a competitive total of 170.
Northamptonshire were behind the rate from the off as Durham's bowlers dominated the second half of the contest.
Imran Tahir led the way with four wickets for 16 runs, while Weighell and Nathan Rimmington notched two wickets apiece, to guide the Jets to a comfortable win and within touching distance of the last eight.
Durham made a ponderous start to their innings, failing to find their feet until the sixth over when three boundaries came off Seekkuge Prasanna's first over.
Tom Latham was the first man to fall when he top edged Luke Procter's first delivery to fine leg where Richard Gleeson took a good low catch.
The Steelbacks limited the home side's progress, and Graham Clark's attempt to cut loose resulted in the opener being bowled by Prasanna for 29.
The arrival of Liam Trevaskis at the crease brought Durham to life as the left-hander blasted two straight sixes to provide impetus. His brisk innings took the pressure off Collingwood at the opposite end, allowing the veteran to find his rhythm.
The wickets of Trevaskis and Ryan Davies threatened to stymie the home side's late push for runs. However, Weighell found his touch immediately, scoring 20 off 14 deliveries.
Collingwood was able to scamper through on tiring legs to reach his half-century off the final ball, getting over the line with the aid of a Ricardo Vasconcelos error.
Northamptonshire struggled in their reply as the Durham attack found their line and length. Rimmington made the breakthrough to dismiss Richard Levi for two off just 10 deliveries.
Weighell then handed the home side control with two strikes in the following over. First he removed Ben Duckett as Trevaskis took a fine catch on the run on the legside boundary before Josh Cobb drove straight to Latham at mid-off.
Tahir kept the pressure on the Steelbacks, pinning Vasconcelos lbw for six, leaving the visitors 31 for four in the eighth over. Steven Crook offered brief resistance with an innings of 21 before Tahir produced a full delivery to send him on his way.
Northants began to unravel quickly in the tail. Procter and Graham White were dismissed by Ryan Pringle and Rimmington respectively before Tahir wrapped up the victory with two wickets in his final over by removing Prasanna and Nathan Buck.
Birmingham Bears notched a first win in five matches as they beat Leicestershire Foxes by eight wickets.
Grant Elliott's team won two of their opening three matches but the first half of their season was otherwise a disappointment and they went into this fixture next to bottom of the table.
But after Olly Stone had shown his quality and potential with a fine display of pace bowling, the Bears dismissed the Foxes for 143 in 19.3 overs.
Adam Hose then took advantage of a dropped catch on 16 to go on to make a 34-ball unbeaten 66.
After Ian Bell - top scorer in the competition so far with 363 runs - had been freakishly run out for 34, Hose and Sam Hain eased the Bears to a win that could hardly have been more comfortable, their 95-run partnership getting the job done with 34 deliveries to spare.
Stone finished with three for 22, taking the key wicket of Mark Cosgrove and came back to stifle the home side's bid to push up the total in the final overs by dismissing Ned Eckersley and Mohammad Nabi in the space of three deliveries.
The Foxes, who won the toss and chose to bat, struggled to build any momentum after losing Cameron Delport to the second ball of the night.
They had some joy against Aaron Thomason's seamers and found Jeetan Patel in a more generous mood than usual but found Elliott and Chris Woakes a much more difficult proposition as both returned figures of two for 18 from their four overs.
Neil Dexter played well for his 56 but the former Middlesex batsman was pinned down after reaching 51 off 29 balls with a huge six over mid-wicket off Patel in the 10th over, who had his revenge when he pushed one through to bowl the opener in the 14th.
Bell, whose T20 form has been outstanding in what has been a productive season all round for the former England batsman, had his eye in from the start, running up half a dozen boundaries in the powerplay as his side raced to 50 for one.
The only casualty to that point had been Ed Pollock, who was unfortunate to be bowled by a ball from Nabi that kept very low, although Pollock's footwork was not the best.
Bell looked in commanding form and it was a bonus for Leicestershire that he was the victim of a freakish dismissal as Callum Parkinson ran him out at the non-striker's end for 34, although the bowler deserves credit for diving in follow-through to get a hand to Adam Hose's firm drive.
By contrast, Zak Chappell deserved no credit at all for letting Hose off the hook in Parkinson's next over, when the batsman, on 16, gave the Foxes pace bowler what should have been a routine catch on the long-on boundary and was relieved to see the ball bounce out of the fielder's hands.
It was a costly miss as Hose went on to take full advantage as the Bears maintained their record of never having lost a T20 match at Grace Road, setting themselves up nicely for a busy weekend that involves trips to Derby on Friday night and Northampton on Sunday.