Top seed Isner crashes out
Top seed John Isner was dumped out of by fellow American Ryan Harrison in the second round of the Apia International in Sydney.
- Related Content
Qualifier Harrison, the world number 68, won the second-round clash 6-4 6-4 in one hour 14 minutes.
The big-serving Isner was broken once in each set as his second serve proved a weakness.
Spain's Fernando Verdasco, the fourth seed, also suffered an unexpected loss, as he went down in straight sets to Denis Istomin.
The Uzbek player won 6-3 6-3 as Verdasco failed to create a single break point.
Fifth-seeded German Florian Mayer and Czech Radek Stepanek, seeded five, made it four seeds knocked out of the men's draw today.
Mayer went down 7-6 (7/4) 6-2 to home favourite Bernard Tomic, while Stepanek was forced to retire just seven minutes into his clash with France's Julien Benneteau with the score 0-0.
"I'm serving really well and my groundstrokes are really good, too. I'm moving really well," said Tomic, who clocked a 207 kph serve during the match.
"There is nothing much more I can ask myself at this stage. I think whereas before I got carried away; I started over-thinking.
"Now it's just who I play on that day. I don't look too much ahead now and just focus on who I have to play and play as best as I can. That's what I'm doing."
Third-seeded Italian Andreas Seppi had to fight to see off Australian wild card John Millman 6-2 3-6 6-3.
Spain's Marcel Granollers, the eighth seed, saw off Fabio Fognini 6-2 7-6 (7/4).
Elsewhere, Finland's Jarkko Nieminen beat lucky loser Ivo Klec of Slovakia 6-3 6-1 and South African Kevin Anderson triumphed over Spain's Feliciano Lopez 6-3 6-4.