Ceiron Thomas booted Leeds to their first Guinness Premiership victory since beating Newcastle in March 2008.
Thomas kicked five goals to settle a tryless encounter 15-9 against Wasps in the visitors' favour.
Wasps were booed off the field after a performance laden with set-piece errors resulted in their first ever defeat by the Yorkshire side.
With World Cup winner Andy Gomarsall probing and prompting at scrum-half, Leeds looked the more accomplished team at a rain-sodden Adams Park.
Newcastle Falcons laboured to a 14-3 win over Worcester Warriors at wet and windy Kingston Park.
Three penalties from the boot of Jimmy Gopperth and a close-range try from hooker Rob Vickers gave the Falcons their second successive Premiership win as Worcester toiled to match Carl Hayman and the Newcastle pack who were in control throughout.
Saracens made it a magnificent seven successive victories in the league after they beat Bath 12-11 to preserve their status as unbeaten leaders.
But while Saracens can look down on the rest, Bath remain in freefall.
They have won just once from nine starts in all competitions, leaving them only six points above bottom club Leeds Carnegie, who have a game in hand.
There was plenty of honest toil from the Bath forwards but little spark in a back division crying out for the return of either Olly Barkley or Butch James.
A late try by captain Michael Claassens, following penalties from Ryan Davis and Jack Cuthbert, meant a tense finish, yet Saracens deserved to take the spoils.
They possessed comfortably the game's most elusive runner in England Saxons wing Noah Cato, whose try just before half-time gave his team a degree of breathing space.
Flanker Andy Saull also crossed for the visitors, rounding off a sweeping early move, and with an aggressive Saracens pack enjoying some raw physical exchanges, Bath could make little headway.
Rory Clegg kicked a last-gasp penalty to earn Harlequins a battling 9-9 draw against London Irish in a war of attrition at the Twickenham Stoop.
All the points in the match came from penalty goals, the most crucial of which was landed by Clegg with the last kick of the game as title-chasing Irish were denied a sixth straight victory.
Prior to that, Clegg and Irish's Ryan Lamb had each stroked over two first-half penalties before Peter Hewat edged the visitors 9-6 in front with a three-pointer in the 72nd minute.
Clegg's late coup de grace means Quins stretch their unbeaten run in the league to four games but Irish lost a great opportunity to keep on the coat-tails of unbeaten leaders Saracens.
Leicester maintained their 13-month unbeaten home record with a 29-15 defeat of Northampton.
Former Ireland fly-half Jeremy Staunton kicked 19 points, including conversions of tries from Lucas Amorosino and Anthony Allen.
Northampton scored two excellent first-half tries, both stemming from menacing runs by Bruce Reihana, but lacked their familiar cutting edge without England pair Ben Foden and Shane Geraghty and managed only a second-half penalty from Stephen Myler.
Martin Johnson was dealt another injury blow ahead of England's autumn internationals after Mike Tindall limped off after just 16 minutes of Gloucester's 28-23 defeat at Sale.
Tindall, who played alongside Johnson in England's 2003 World Cup-winning side, appeared to have suffered a recurrence of the hamstring injury which had ruled him out of Gloucester's previous three matches.
While Johnson's problems are mounting, life is not getting any easier for Gloucester head coach Bryan Redpath - whose side lost despite outscoring Sale by three tries to one.
Gloucester's notorious disciplinary problems surfaced again in the 35th minute when Tindall's replacement, Charlie Sharples, was shown a red card and flanker Andy Hazell and prop Paul Doran-Jones were also lost to injury.
Yet despite playing for more than half the match with a man less, Gloucester refused to buckle and hauled themselves right back into the match in the 66th minute with a converted try from Will James.
Greg Somerville went over with two minutes remaining but it was not enough to avoid a third successive defeat as Sale eased the pressure on director of rugby Kingsley Jones after a powerful first-half display saw them establish a 16-8 lead.