The early fixture list has not been kind to Castleford with Super League champions Leeds Rhinos next up for the Tigers.
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Ian Millward's men kicked off the campaign with a tough trip to Warrington Wovles and while they were put to the sword early on they did restore some pride in a 40-24 loss.
Brian McDermott's Leeds were being held by Hull FC at Headingley for 55 minutes before a late collapse from the visitors from East Yorkshire saw the home side prevail 36-6.
Leeds have won their last six meetings against the Tigers. Castleford have lost four straight league matches at home to their neighbours - their last success was a 38-20 win in 2008.
Castleford head coach Ian Millward has brought Wales international forward Dan Fleming into his squad. Kirk Dixon remains sidelined with a calf muscle tear.
Former Leeds second rower Weller Hauraki is one of five players making their home debuts while full-back Jordan Tansey will also be facing his former club.
"There's no better feeling than playing Leeds Rhinos here at Cas, especially when the fans are all fired up for it," said centre Michael Shenton.
"It feels like a bigger game than normal playing Leeds, who are the champions, but we can't get too carried away with the occasion. If we show the patience we showed during parts of the game against Warrington, we won't go far wrong."
Leeds have called up German youngster Jimmy Keinhorst in place of injured winger Joe Vickery. Vickery departed the field in the first half of his Super League debut against Hull FC.
Prop Kylie Leuluai has also been included in McDermott's initial squad after he was prevented from playing for Hunslet Hawks on dual-registration terms.
Jamie Peacock, who joined Leeds from Bradford in 2006, is set to make his 200th appearance for the club while Danny McGuire has scored 22 tires in 19 games against the Tigers.
Castleford: Owen, Carney, Shenton, Webster, Chase, Ellis, Walker, Clark, Huby, Gilmour, Hauraki, Millington, Milner, Massey, Holmes, Thompson, Tansey, Fleming, Mason.
Leeds: Hardaker, Watkins, Moon, Hall, McGuire, Burrow, Leuluai, McShane, Peacock, Jones-Buchanan, Ablett, Sinfield, Ward, Delaney, Bailey, Kirke, Clarkson, Achurch, Keinhorst.