Mustajeeb further franked Kingman's Irish 2,000 Guineas form with a game victory in the Group 3 Jersey Stakes, the opening race of the second day at Royal Ascot.
The Nayef colt, trained in Ireland by Dermot Weld, came home ahead of another Hamdan Al Maktoum runner Muwaary with Aidan O'Brien's Giovanni Boldini back in third.
It proved beneficial to be up with the pace from the off, with the first three all in the front five as the field passed halfway, led by the previously unbeaten That Is The Spirit.
Winning jockey Pat Smullen made his move to the front around the three furlong marker and the 9/2 joint favourite found plenty for his urgings as Muwaary launched his bid.
But he could get no closer than a length at the line as the bookmakers again suffered - he was the other 9/2 joint favourite.
The pair were nicely clear of 14/1 shot Giovanni Boldini with Windfast and Waltzing Matilda also close up.
Mustajeeb won the Group 3 Amethyst Stakes at Leopardstown last month before finishing third, seven lengths behind Tuesday's St James's Palace Stakes winner Kingman, in the Irish 2,000 Guineas at The Curragh.
Smullen said: "I couldn't believe how well it worked for us. There wasn't a great deal of pace early and I just got him to get on the bridle and travel. Once I was there (in front) I was never going to take him back as we knew he'd stay all the way to the line.
"He's not a slow horse and, to be fair, he had some solid form coming into the race. It's beautiful good ground, perfectly safe and this horse really relished it."
Weld commented: "Kingman is an outstanding miler and we were beaten fair and square in the Irish Guineas.
"This colt really appreciated the better ground today, I thought he'd win and he did it well.
"He's a very genuine, tough, nice colt. It's nice for Sheikh Hamdan, he's a home-bred horse and it's lovely for Sheikh Hamdan to have the one-two.
"This has been a very consistent horse for us. He's a good Group winner over a mile and he'll probably go back to a mile in the future. He's a horse to look forward to."