Noble Mission again claimed the scalp of Telescope to win the Betfair Price Rush Huxley Stakes at Chester.
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Lady Cecil's charge, a full-brother to Frankel, had his Sir Michael Stoute-trained rival well in arrears when winning at Sandown last time and confirmed his superiority here - albeit by a reduced margin.
It was a noteworthy performance from the 9/4 favourite who was harried for the early lead by Ektihaam and still had the reserves to fend off Telescope (5/2) as he tried to challenge inside the final two furlongs.
At the line two-and-a-half lengths separated the pair.
Jockey James Doyle, whose companion was carrying a 3lb penalty, said: "He just proved that he doesn't have to be in front the whole way.
"I'm chuffed to bits with him. He's a solid Group horse and always tries his best. He has been called names, and all the rest of it, but it's hard to fault him there."
Lady Cecil said: "I had no reason not to run him because he was in such great form. Over the winter, he did so well. He just seemed better and stronger. We just thought this year he would find a lot more improvement.
"The aim is to get a Group One, but to have those two Group Threes is good. He's remarkably consistent. I think he's probably got an unfair reputation.
"He's in the Hardwicke and it's always nice to have a runner at Royal Ascot. It's not for certain, but that will probably be his next target. He deserves a bit of a break."
Teddy Grimthorpe, racing manager to winning owner Khalid Abdullah, said: "Sandown was a bit messy, as he was against unfit horses on testing ground.
"He had to fight to get a lead today and it wasn't easy as he was pushed wide, but he was happy in front and settled, then he got a little breather and went again.
"We were considering the Huxley against the Ormonde and decided on this as we thought it was best for the horse. The Hardwicke is a possible, but we will have to look at the options."
Racing manager Harry Herbert said of the Highclere Thoroughbred-owned Telescope: "He has run well and to be honest he has been beaten by a better horse on the day.
"I'll talk to Sir Michael (Stoute), but we will probably step up to a mile and a half on a more galloping track and I think the Hardwicke will be a likely option.
"He's got a long season ahead and I'd say he's coming, but today he's been beaten fair and square."