The Fugue produced a devastating turn of foot to put her rivals to the sword in the Darley Yorkshire Oaks at York on Thursday afternoon.
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Long-time leader Scintillula set a decent gallop under Kevin Manning but she gave way to her rivals at around the three furlong marker. The 9/4 second-favourite Venus De Milo took up the running with two furlongs to go but she was always a sitting duck as William Buick exuded confidence on the 2/1 market-leader.
She put the race to bed in a matter of strides when Buick asked the question and she gamboled away to register a four length victory.
Buick could not disguise his delight after the race.
"I'm delighted for the filly as she's showed everyone what she can do," he said.
"They went a good gallop up front and it's sometimes difficult to make the ground up when it's quick. She loves this ground though and is top class when it's like this."
The Fugue's trainer John Gosden was notably relieved after the his filly had recorded the second Group One victory of her career.
"It's lovely to have a nice home-bred filly like this," said Gosden. "I'm happy for her as I thought she'd get very near to the colts in the Eclipse but she was very ill afterwards and that wasn't her running.
"We had to miss the Nassau as a result but it meant she was on top form for this race and it's all come right. In truth, we really should have won last year as she came to win the race but a driving thunderstorm meant the jockeys couldn't see what they were doing.
"I thought she had it won but she was just nailed on the line. She's made up for it this year though."
Venus De Milo plugged on to finish second while 6/1 shot Secret Gesture was back in third. The Fugue has been chalked up at 12/1 for the Prix de l'Arc de Triomphe, which could be an option for the four-year-old along as is a trip to California for the Breeders' Cup.
The Fugue finished a luckless third at Santa Anita in last November's Filly & Mare Turf over the turning mile and a quarter, and this year could take on the boys over a mile and half in the Breeders' Cup Turf.
Gosden said: "The Vermeille (Longchamp, September 15) would come into consideration for her next run and after that there is the Arc and I do think she is that level. If the ground is good or faster, or even good to soft, that would be a strong possibility, but she hates bottomless ground.
"She went to the Breeders' Cup last year and didn't have much luck, but we'd be keen to go back. There is the Filly & Mare, but the mile-and-a-half race (Breeders' Cup Turf) could be more suitable for her."