Flotilla became the first European winner of the Breeders' Cup Juvenile Fillies Turf after swooping late under Christophe Lemaire.
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Her trainer Mikel Delzangles is facing up to a huge few days in America and Australia and his charge here powered down the centre of the track to reel-in the leaders in the final furlong.
Watsdachacnes held on for second with Summer Of Fun a fast-finishing third.
Sky Lantern travelled better than any of her rivals turning for home but Richard Hughes' partner ran out of room down the inside and finished full of running in mid-division.
Delzangles said: "I was surprised how well she settled here. I was not confident she would win but thought she would run a good race.
"Hopefully she will be a Classic filly in Europe next year."
Lemaire said: "In the mornings she can be a little bit keen. She can be quite forceful and the pace was not very strong but she had plenty in hand. When I put her out she accelerated very well and I think she won easily.
"She was on the bit today because of the slow pace, so that's why I was a bit worried, but she was much better than the others."
Richard Hughes, rider of the Richard Hannon-trained Sky Lantern, said: "She jumped out really well, but when I came round the bend I was stuck with nowhere to go."
The trainer's son, Richard Hannon jnr, said: "She came round the turn in a perfect position, but when she tried to get out Hughesie was forced back twice. She never came off the bridle."
It was a similar story for the other European raiders.
Frankie Dettori, unplaced on Ralph Beckett's Waterway Run, said: "I went for half a gap and straight away I was pushed back. It might have cost me third, but I was delighted she ran well."
Jeremy Noseda, trainer of The Gold Cheongsam, said: "I feel with a better and clearer run she would have gone close. We knew we were up against it from the 12 slot, but she flew home."
Aidan O'Brien's Infanta Branca was out of luck after coming in as first reserve when Sustained was scratched.
O'Brien said: "She ran a great race and I'm very happy with her especially as she doesn't have much experience. We can look forward to her next year."