Golds for O'Connor and Halsall
England's Siobhan-Marie O'Connor and Fran Halsall added to their impressive Commonwealth Games medal hauls with golds on another memorable night of action in the Tollcross pool.
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O'Connor claimed her fifth medal of the Games - and her first gold - by storming home in the 200 metres individual medley and Halsall later set a new Games record as she took gold in the 50m butterfly final.
Scotland were also savouring success as 13-year-old Erraid Davies and her hero, Hannah Miley, both claimed bronze.
Davies, Scotland's youngest-ever Comonwealth Games competitor, was roared into the medal positions in the para-sport 100m breaststroke SB9 final and Miley finished behind O'Connor to add the bronze to her gold in the 400m individual medley.
And the host nation almost saved the best until last when their men's 4x200m freestyle relay team pushed hot favourites Australia all the way before claiming a silver amid deafening cheers.
England also had a bronze to celebrate as world-record holder Liam Tancock finished behind Australian pair Ben Treffers and Mitch Larkin in the 50m backstroke.
Davies claimed the first home medal of the night and O'Connor soon took gold to add to the three silvers and bronze she had already won at Glasgow 2014.
The 18-year-old finished more than two seconds ahead of Olympic runner-up Alicia Coutts of Australia to set a Games record of 2:08.21.
"I wasn't sure I had it in me but I'm absolutely over the moon so that was a dream," she said. "Sport is so full of ups and downs.
"This is definitely what I do it for. It's all about making the sacrifices and I have made a lot to be here. But it's worth it - such an incredible feeling."
Miley surprised herself by taking bronze ahead of England's Aimee Willmott.
"It's been an amazing meet and I don't really know where that performance came from," she said. "I really thought I'd be outside the medals in fourth or fifth so to go one better than that and come away with some hardware is pretty special."
Halsall's victory was her third gold of a total of 10 Commonwealth medals.
The Southport-born 24-year-old, who earlier qualified for the 100m freestyle final, said: "I remember being in Melbourne (in 2006) and swimming the 100m freestyle final and there was Libby Lenton at the time, Trickett now, Jodie Henry and Alice Mills.
"They were the top three in the world and I came fourth to them. I thought, 'how am I ever going to swim that fast to beat those girls?'
"Now, I have got my own Commonwealth gold medals so I am really happy."
Tancock claimed his ninth Commonwealth medal but the hosts almost stole the show in the final race. Gold medallist Daniel Wallace led them off in a stunning challenge to Australia and Scotland were neck and neck after Robbie Renwick set off on the final leg, but Thomas Fraser-Holmes moved away to knock almost three seconds off the Games record.
Earlier, Shetland schoolgirl Erraid Davies won a bronze medal in the women's 100m breaststroke SB9 final after the 13-year-old set a new personal best for the second time in a day.
Scotland's youngest-ever Comonwealth Games competitor had come second in the heat on Sunday morning and fought her way into the medal positions in the last quarter of the final.
Roared on by the Tollcross crowd, she finished just behind Australian silver medallist Madeleine Scott in one minute and 21.38 seconds, with New Zealand's Sophie Pascoe taking gold.
It was another case of nearly but not quite for England's Lizzie Simmonds as she finished fourth in the 200m backstroke final with Australia's Belinda Hocking the winner.
The 23-year-old, who came fifth in the 100m final and fourth in the Olympic 200m final in 2012, said: "I wanted to be in the medals. I am not going to lie, I should have been there. I am quite upset about it."
Adam Peaty saw his 50m breaststroke Games record vanish hours after setting it when South African world-record holder Cameron van der Burgh finished in 26.80secs in the first semi-final.
But the English teenager, who managed just three hours' sleep in between winning the 100m gold on Saturday night and returning to Tollcross for his morning heat, knocked one-hundredth of a second off his new British record as he won the second semi-final in 26.99. Mark Tully was the fastest of three Scots to qualify for Monday's final ahead of 200m gold medallist Ross Murdoch and Joe Welstead.
Australia continued their domination of the men's freestyle events with a clean sweep of the 100m final, James Magnussen taking gold with England's Adam Brown in medal contention until the final 25m before finishing sixth.
Welsh swimmer Jazz Carlin earlier set a new Games record in qualifying for Monday night's 800m freestyle final, finishing more than 11 seconds ahead of her nearest rival in 8:22.69.
England's Adam Barrett finished fastest in the 100m butterfly semi-finals ahead of 200m gold medallist Chad Le Clos while Yorkshire teenager Sophie Taylor won both her heat and semi-final in the 100m breaststroke.