| Week 4 |
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| Sunday, Oct. 4 |
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| Detroit Lions 24-48 Chicago Bears |
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| Cincinnati Bengals 23-20 Cleveland Browns (OT) |
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| Oakland Raiders 6-29 Houston Texans |
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| Seattle Seahawks 17-34 Indianapolis Colts |
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| Tennessee Titans 17-37 Jacksonville Jaguars |
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| N.Y. Giants 16-27 Kansas City Chiefs |
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| Baltimore Ravens 21-27 New England Patriots |
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| Tampa Bay Buccaneers 13-16 Washington Redskins |
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| Buffalo Bills 10-38 Miami Dolphins |
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| N.Y. Jets 10-24 New Orleans Saints |
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| Dallas Cowboys 10-17 Denver Broncos |
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| St. Louis Rams 0-35 San Francisco 49ers |
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| San Diego Chargers 28-38 Pittsburgh Steelers |
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| Monday, Oct. 5 |
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| Green Bay Packers 23-30 Minnesota Vikings |
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| Byes: Arizona, Atlanta, Carolina, Philadelphia |
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