United out to 8/1 as rivals win
Manchester United are out to 8/1 with Sky Bet for the title after losing ground on their rivals on the opening weekend.
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Louis van Gaal's first competitive game in charge saw him side slump to a 2-1 defeat to Swansea at Old Trafford, which saw them eased in the outright market.
Wins for Arsenal, Liverpool and Manchester City followed, and come 1830 BST on Sunday evening United were fifth in the betting at 8/1 having been 9/2 before the season began.
Arsenal's victory came courtesy of a late Aaron Ramsey strike and they're into 9/2, while Liverpool were trimmed a point to 10/1 following a hard-fought win against Southampton.
City were the only ones to cover a one-goal handicap in beating Newcastle 2-0 thanks to goals from David Silva and Sergio Aguero, and they remain second-favourites at 9/4.
Chelsea hardened to a general 7/4 without playing, with their first game coming at Turf Moor on Monday night against promoted Burnley.
The Clarets remain the only side odds-on for relegation but QPR were cut to 7/4 following their defeat to Hull, while Crystal Palace were trimmed to the same price after they eventually succumbed to Arsenal.
Leicester went from 11/4 to 3/1 having secured a point against Everton, a result which saw the Toffees eased to 8/1 for a top-four finish.
With City and Chelsea considered virtual locks, Arsenal (2/5), United (8/11) and Liverpool (8/11) appear likely to fight for two spots in the Champions League although Tottenham (3/1) are also contenders following their 1-0 win at West Ham on Saturday.
The other market which saw action over the weekend was the Golden Boot betting, with Aguero into 9/2 and Daniel Sturridge just 5/1 after both started the season in fine fashion.