Neil Taylor out for the season
Swansea defender Neil Taylor will miss the rest of the season with a broken ankle.
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The 23-year-old full-back suffered the injury in the 20th minute of Saturday's draw with Sunderland, and was immediately taken to hospital.
3. Neil Taylor
The Wales international has since had surgery and it has been confirmed that he has broken and dislocated his ankle in three places.
"The surgeons worked hard on Neil's injury last night and did a very good job," said Swansea's head physio Kate Rees on the club's official website.
"He is comfortable and the surgeons are happy with the operation.
"While he should make a full recovery, the extent of the injury means Neil is likely to miss the rest of the season."
Roberts, who joined the Swans from Wrexham last summer, had appeared in all three of the club's Premier League games this season, having enjoyed a successful debut season in the top flight.
With Taylor injured, Wales manager Chris Coleman has now lost three of his first-choice starting XI ahead of the start of their World Cup qualifying campaign against Belgium on Friday.
Brighton midfielder Andrew Crofts joins Taylor on the sidelines after picking up an ankle injury while Cardiff striker Craig Bellamy is the third player to be withdrawn from the squad due to a calf injury.
Bellamy's Cardiff team-mate Rob Earnshaw is the only person to have been called into the squad as cover.
Coleman has already been hit hard by injury problems with Celtic's Joe Ledley (groin), Sunderland's David Vaughan (groin), Wolves keeper Wayne Hennessey (knee) and West Ham's Jack Collison (knee) all absent from his initial 23-man selection.
Uncapped Crystal Palace midfielder Jonathan Williams was included in the squad, as was Leicester's Andy King.
Key trio Gareth Bale, Joe Allen and Aaron Ramsey are all available for the daunting clash with a Belgium squad including the likes of Vincent Kompany, Marouane Fellaini and Eden Hazard.