Real Madrid will be without world-record signing Gareth Bale ahead of their crunch La Liga trip to Athletic Bilbao.
- Related Content
The £87million Welshman has been nursing a leg problem and missed the 1-0 win over Espanyol in the Copa del Rey quarter-finals in midweek.
It is the latest of a number of frustrations for Bale, who has completed the 90 minutes just nine times in 30 competitive games this season.
Madrid boss Carlo Ancelotti confirmed on Saturday afternoon that Bale would be absent for the Bilbao match - but believes he will be fit for the Copa del Rey semi-final showdown with Atletico in midweek.
"He's not available because he didn't train throughout the week with the squad," said Ancelotti.
"He's done a good job today, he'll train tomorrow and I think he'll be available for Wednesday."
With the Wales International absent, former Academy player Jese - who stood in for Bale and scored the winner against Espanyol - could again feature.
Ancelotti said: "We have two options to replace Bale: Jese, who is doing very well and who we have a lot of confidence in, or (Angel) Di Maria on the right and (Asier) Illarramendi in the middle."
Real will travel in good form having won all of January's eight games unbeaten without conceding a goal.
Ahead of this weekend's round of games they are third in the table but just a point behind joint-leaders Barcelona and Atletico Madrid.
Fourth-placed Bilbao could provide a stern test, however, having won their last three league matches impressively.
Ernesto Valverde's men were beaten by Atletico Madrid in the Copa del Rey this week but confidence should still be high after beating Almeria, Real Valladolid and Osasuna by scorelines of 6-1, 4-2 and 5-1 respectively in La Liga.
Valverde said: "We are playing very well at the moment and doing some very good things, so I don't think this (cup loss) will cost us dearly."