Lille will have to face Marseille on Sunday without their influential midfielder Florent Balmont who is suspended.
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Balmont has played a key role in Lille's successful season so far which sees Rene Girard's on the brink of Champions League qualification.
Lille are in third spot in Ligue 1 with a useful gap over the chasing pack and Sunday's match at sixth-placed Marseille could prove pivotal to their season.
Les Dogues are unbeaten in 10 matches and have been 1-0 win specialists this season - nine victories have come via that scoreline including against Valenciennes last weekend.
Girard said: "We will go to the Velodrome in a relaxed frame of mind, still with our little cushion of points which means we have no obligation other than to try and take something from Marseille.
"Psychologically, it is also important to maintain the gap down to fourth spot. We know that we will not have an easy end to the season with Marseille, Bordeaux, Bastia, Paris and Lorient all to come. It's tough, but at least it ensures that the lads will remain focused."
Lille have full-backs Franck Beria and Pape Souare back from bans but Marseille will be without left-back Jeremy Morel who is suspended.
Marseille have endured a troubled season but still have an eye on the Europa League after two wins on the trot including against Montpellier last week.
Striker Andre-Pierre Gignac told www.ligue1.com: "Winning a second match in a row eases the tension. We battled hard and beat Montpellier because we kept things simple. I hope we can do the same in the big match against Lille. Our aim is to give our fans a great end to the season and qualify for Europe."