Dani Osvaldo, Luke Shaw, Nathaniel Clyne and Kelvin Davis could all return for injury-hit Southampton at Cardiff on Boxing Day.
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The quartet will have various injuries and ailments assessed on Christmas Eve to see whether they are able to return for the Barclays Premier League clash in south Wales.
Jose Fonte and Maya Yoshida were on the bench for Sunday's 3-2 defeat to Tottenham due to slight problems, while Artur Boruc (hand), Victor Wanyama (shin) and Guly do Prado (knee) remain sidelined.
Craig Bellamy looks set to miss out as the veteran forward continues to struggle with a knee problem.
Manager Malky Mackay may decide to restore Fraizer Campbell to his starting line-up having left the striker on the bench for the weekend defeat at Anfield.
Kim Bo-kyung is also pushing for a recall to the starting XI, and could come into the side at the expense of Aaron Gunnarsson.
Cardiff (from): Marshall, Connolly, Taylor, Caulker, Hudson, Turner, Whittingham, Medel, Cornelius, Campbell, Odemwingie, Brayford, Kim, Smith, Noone, Gunnarsson, Mutch, Cowie, Maynard, Theophile-Catherine, Lewis, John.
Southampton (from): K Davis, Gazzaniga, Cropper, Chambers, Clyne, Shaw, Fox, Fonte, Hooiveld, Lovren, Yoshida, Cork, Schneiderlin, S Davis, Ward-Prowse, Reed, Ramirez, Rodriguez, Lallana, Gallagher, Osvaldo, Lambert.