Captain Brede Hangeland is expected to miss Fulham's game against Southampton on Saturday because of a nerve injury in his leg.
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Manager Martin Jol said the centre-back will probably sit out the game at St Mary's while midfielder Bryan Ruiz is doubtful because of a back injury.
Defender Aaron Hughes could make his first appearance since August 31 if he overcomes a thigh injury, but full-back Matthew Briggs (hernia) is still out.
Midfielder Steven Davis is a doubt for Southampton. The Northern Ireland captain picked up a knock in the draw against Manchester United last weekend and he faces a late fitness test.
"Steven has a slight problem," said Southampton manager Mauricio Pochettino.
"He will be looked at by the medical services and we will see if he can play on Saturday."
Midfielder Gaston Ramirez could return to the squad after missing out last weekend.
Southampton team (from): Boruc, Clyne, Fonte, Lovren, Shaw, Schneiderlin, Wanyama, Lallana, Steven Davis, Rodriguez, Osvaldo, Kelvin Davis, Lambert, Ward-Prowse, Cork, Guly, Chambers, Hooiveld, Ramirez, Yoshida, McCarthy, Stephens.
Fulham team (from): Stekelenberg, Stockdale, Richardson, Hughes, Hangeland, Riether, Amorebieta, Sidwell, Karagounis, Parker, Kacaniklic, Ruiz, Kasami, Bent, Taarabt, Berbatov, Etheridge, Senderos, Zverotic, Rodallega.