Lazio will head to the Juventus Stadium in confident mood on Saturday, hoping to follow the example of Inter Milan and become only the second side to win at the Turin club's new home.
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The Nerazzurri reopened the Serie A title race with a 3-1 away win over the Bianconeri a fortnight ago and, although Juve bounced straight back with a 6-1 win at Pescara - a result which, combined with Inter's loss at Atalanta, restored their four-point lead - Lazio coach Vladimir Petkovic still believes his team have a chance this weekend.
"Juve are favourites for the Scudetto, but we are capable of beating them in Turin," said Petkovic, whose side's hopes have been boosted by the suspension of influential Juve midfielder Andrea Pirlo.
"To do it, we are going to have to play 20-30 per cent better than we did in the derby (Lazio beat Roma 3-2 last weekend), which is the only way of beating them in their own stadium."
Petkovic hopes to be able to field striker Miroslav Klose, who has never scored against Juve, even though the Germany international remains under the weather after a bout of flu.
"He is sick and is coughing, so we have got to be careful," Petkovic added. "He is not in top condition, but his dedication to this club is incredible.
"He has trained, despite not being well, and it was pointless him going off to play for his country."
Klose remained in Rome this week after dining with Joachim Low in the Eternal City last Sunday night after the Germany coach had been to check up on his progress in the Rome derby.
It remains touch and go whether the Biancoceleste's top scorer will be able to try to break his duck against Juve, but the absence of Pirlo on the other side is certain.
The Italy international is suspended and will miss his first league game of the season, providing 19-year-old French midfielder Paul Pogba with an opportunity to stake a claim for a more regular place in the side.
"He is a very confident lad, but never arrogant. He is just sure about what he is doing," Juve coach Antonio Conte said in a chat with fans on the club's website. "Pogba will become the best player in the world."