Peterborough manager Darren Ferguson could hand a debut to defender Ryan Bennett as Scunthorpe visit London Road.
Ferguson signed the defender on Friday from Grimsby after failing with two bids in the summer and he could start.
First-choice left-back Tom Williams remains sidelined with the ankle injury he picked up against Bristol City last weekend.
Midfielder Paul Coutts is still out with a foot injury while winger Sergio Torres is now back from his loan spell at Lincoln.
Utility man Charlie Lee made his return from an ankle injury as a substitute at Ashton Gate last weekend and after scoring twice for the reserves in midweek will hope to force his way into the starting XI.
Ferguson's men last won in the league over a month ago and remain in the relegation zone.
Striker Gary Hooper is an injury concern for Scunthorpe's trip.
The former Southend frontman injured his ankle in the midweek victory against Newcastle and will undergo a late fitness test.
If Hooper misses out, boss Nigel Adkins could opt to play Paul Hayes as a lone striker or Jonathan Forte could get the nod to play in attack.
Michael O'Connor returns from suspension, but Martyn Woolford will be hopeful of retaining his place in midfield after scoring both goals in the 2-1 triumph over the Magpies.
Midfielder Josh Wright came through Tuesday's game unscathed after picking up a knock last weekend and the former Charlton man is expected to start once again.
Ben May (ankle) and Kenny Milne (knee) are still sidelined through injury.