Power pay out on Man United
Paddy Power became the first bookmaker to pay out on Manchester United winning the Premier League on Sunday.
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Manchester City's 3-1 defeat to Southampton on Saturday evening prompted the decision.
The Irish firm actually paid out before United beat Everton 2-0 to stretch their lead at the top of the table to 12 points with 12 games to go.
Power said they were so confident United would go on to win a record 20th championship that they paid out more than £500,000 to United backers.
After goals from Ryan Giggs and Robin van Persie gave United their win, Betfred joined Power in paying out on Sir Alex Ferguson's men.
History suggests the decisions could backfire.
Last season United blew an eight-point lead with six games remaining - after Betfred had declared the Red Devils champions - while Betfred founder Fred Done famously paid out on United in 1997/98 before Arsenal pipped them to the title.
In addition, City have still to visit United in April, while the Blues do not have the distraction of European football to worry about.
A spokesperson for Paddy Power said: "The fat lady might not be singing yet but she's definitely getting warmed up.
"We can't see United letting their lead slip and with Real Madrid to come in midweek we thought we'd take some of the pressure off Fergie and give punters an early payday."
By Sunday evening, United were a best of 1/25 in the title market with City out to 18/1 at bet365.
Sunday's other game saw Aston Villa beat West Ham 2-1. they were duly pushed out to evens for relegation.
The win moved them out of the Premier League's drop zone with Stan James and BetVictor offering evens about them playing Championship football next season.
Ladbrokes go a best of 10/11 about Paul Lambert's men staying up.
Coral's Nicola McGeady said: "Today's result was a vital win for Lambert and his men, and no doubt fans will be feeling a huge sense of relief. We have cut their odds on survival for now but whether or not they can continue their winning ways is still very doubtful."
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The market now suggests the current bottom three - QPR, Wigan and Reading will be the sides to go. All three lost on Saturday.
QPR, seven points from safety, were no better than 1/4 (Stan James) for relegation on Sunday evening. Reading, a point behind Villa, were 8/13 (Coral) and Wigan, three points below the dotted line, 3/4 (Boylesports).
The prices are beginning to make it look like three from four to go down with Southampton next in the betting at 6/1 (Stan James).
After a poor display, West Ham were cut into a best of 18/1 with bet365. The loss left them seven points above the relegation zone.